Mitochondrial Genetic Disorders: Challenges & Opportunities
نویسندگان
چکیده
منابع مشابه
Mitochondrial Genetic Disorders: Challenges & Opportunities
Due to the close proximity of the mitochondrial genome to the respiratory chain complex producing ATP, it is believed to be more susceptible to get damaged by the reactive oxygen species (ROS) than nuclear DNA. In addition to this, the poorly developed mitochondrial DNA (mtDNA) repair machinery and the lack of protective histones, unlike in nuclear genome are also believed to be the major facto...
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ژورنال
عنوان ژورنال: SOJ Pharmacy & Pharmaceutical Sciences
سال: 2015
ISSN: 2374-6866
DOI: 10.15226/2374-6866/2/1/00119